Free Shipping over $800. Shipping Information
How long does it take to get my order?

Shipping is now FREE on all orders over $800! All other orders incur a $50 shipping charge.

Our Shipping Policy

Any order placed through Medical Spa Rx is shipped out the same day the order is placed, provided the product is in stock, your account is verified and the order is placed before 6:00EST. Your orders through Medical Spa Rx ship only with express shipping companies, which ensures you get your goods in a timely manner without every having to worry about how your package has been treated. When shipping, your goods are taken care of the way they should be. Even when we do not charge you for shipping, we spend the extra money to ship your goods with a courier because we do our very best to make sure you get your order safely and quickly. Just because you are getting a great price does not mean you should have to compromise on the service that you receive.

CALECIM® Professional Restorative Hydration Cream

$129 USD
The origin of this product is
Manufacturer Cellresearch Corporation Pte. Ltd.
Active Substance(s) CALECIM® Rejuvenating Conditioned Media
Strength N/A
Pack Size 1-50g jar
Packs For each
1 - 5 $ 129.00 USD
6 - 10 $ 129.00 USD
11 - 20 $ 129.00 USD
21 - 50 $ 129.00 USD
51+ USD$ 129.00 USD 129
Group Buy $ 129.00 USD


CALECIM Restorative Hydration Cream is packaged in a 50g jar. Launched in February 2017, Calecim Restorative Hydration Cream is a product of CALECIM Cosmeceuticals, a biotech company based in Singapore.

Main Benefits

Incorporated with the innovative trans epidermal delivery technology, CALECIM Restorative Hydration Cream is an anti-aging moisturizer like none other. Thanks to the powerful active ingredients in the Rejuvenating Conditioned Media, CALECIM Restorative Hydration Cream dramatically enhances skin firmness and volume for more resilient skin. Having anti-aging properties, the cream also corrects the appearance of fine lines and shadows, thereby restoring youthful radiance and glow.

Resulting from daily environmental stressors, dehydration is one of the major contributors to skin aging. Over time, skin dehydration can lead to the decomposition of collagen fibers and elastic in the dermal layers of the skin, causing premature aging in young individuals. Specially formulated for dry skin, the cream boosts the natural moisture of the skin to create a younger-looking complexion. The dual-action cream seals the skin barrier to prevent water loss through while allowing the potent ingredients in the conditioned media to penetrate deep into the dermal layers. This helps to retain the natural moisture, leading to a more radiant appearance. On a cellular level, the ingredients in the conditioned media promote skin rejuvenation to revive stressed and tired skin.

Targeting all layers of the skin, the fast-acting formulation delivers visible results in just 14 days, with full results seen in about 3 months.


CALECIM Restorative Hydration Cream is fortified with the patented CALECIM Cord Lining Conditioned Media (30%), which is developed based on ten years of stem cell technology research. In addition, each bottle of Calecim Restorative Hydration Cream is formulated with naturally-occurring hyaluronic acid and skin restoring potent proteins. The preparation also contains several other anti-aging ingredients such as aloe vera, tocopherol, glycoproteins, peptides, soluble collagen, fibronectin, and albumin.

Ingredient Information

Rejuvenating Conditioned Media, the key ingredient of the cream, helps to restore the epidermal cell cycle of the skin, thereby promoting the regeneration of new skin cells. CALECIM Restorative Hydration Cream is also infused with natural hyaluronic acid sourced from the extracts of umbilical cord lining. Having water retention properties, hyaluronic acid plumps up the skin by binding to water molecules. Plus, it contains albumin, fibronectin and skin-supporting collagen, which are delivered through glycoproteins or peptides. Fibronectin increases the strength of collagen by binding to it while albumin helps to enhance skin fullness. Soluble collagen, on the other hand, is able to provide the skin with strength. Glycoproteins and peptides are essential for intercellular crosstalk (or inter-cell signaling).

Other ingredients of CALECIM Restorative Hydration Cream include tocopherol and aloe vera. Tocopherol exerts a protective effect on the skin, helping to prevent trans-epidermal water loss. Having anti-inflammatory and antioxidant properties, aloe vera is able to hydrate the skin’s epidermal layer.

Use Instructions

How do I use or apply this product?

CALECIM Restorative Hydration Cream should be used as in combination with other CALECIM products as part of a daily skincare routine. Having a light texture, the cream is designed to be worn over the corrective treatment. The cream can also be incorporated into the post-procedure skincare regime.

Prior to use, patients should cleanse the face thoroughly. For normal-to-oily skin, the cream should be used after cleansing and toning. CALECIM Restorative Hydration Cream should be used in conjunction with a sunscreen in the morning.

To apply CALECIM Restorative Hydration Cream, spread small amounts of the product over the entire face. Then, pat the skin lightly.

When should I use this product?

For best results, it is recommended to use CALECIM Restorative Hydration Cream every morning and evening. CALECIM Restorative Hydration Cream is also suitable to be used after an aesthetic procedure.

What areas can I treat with this product?

CALECIM Restorative Hydration Cream can be used on thin skin, rough epidermis, and fine lines. In addition, the cream is suitable for skin that is aging prematurely. CALECIM Restorative Hydration Cream is dermatologist tested and suitable for all skin types. This includes normal, dry, combination and even sensitive skin. The unique formulation protects the skin membrane while delivering its active ingredients deep into the skin, offering optimal hydration for dry skin.

How long does the product last?

Rich in rejuvenating ingredients, CALECIM Restorative Hydration Cream delivers superior anti-aging results that last. For long-term benefits, use the cream consistently (preferably two times a day). 

How long does the treatment take?

It is advisable to use CALECIM Restorative Hydration Cream in the morning and evening. For optimal outcomes, use the cream on a regular basis.

Frequently Asked Questions

Where can I order this product for my medical spa?

Purchase CALECIM Restorative Hydration Cream online at Alternatively, you may place your order via email, fax, or phone. Simply contact our customer service team to place a phone order. To order CALECIM Restorative Hydration Cream from Medical Spa RX, simply register an account on our website with your medical license number. If you need help placing an order, feel free to contact our friendly customer representatives.

Why should I order this product?

Order this restorative skincare cream to help your patients correct skin concerns caused by aging.

Who would be interested in buying this treatment at my medical spa?

CALECIM Restorative Hydration Cream is ideal for patients with prematurely aged skin. It is also perfect for patients with a dry skin. Rich in hydrating and rejuvenating ingredients, CALECIM Restorative Hydration Cream is suitable patients who have undergone aesthetic treatments. Designed for all skin types, the cream is the perfect solution for fine lines and other signs of aging. CALECIM Restorative Hydration Cream can be prescribed for those who want to improve their skin firmness and volume.

What side effects can this product cause?

CALECIM Restorative Hydration Cream is dermatologist tested, therefore has a minimal risk of causing untoward reactions. As a general rule, the cream should not be used in patients with a known allergy to any of the active ingredients or excipients in the formulation.
There are no reviews yet

Be the first to review “CALECIM® Professional Restorative Hydration Cream”

Reviews are written by customers who have made verified purchases of this product.

Log in to post your comment!

People who bought CALECIM® Professional Restorative Hydration Cream also bought this

Reset your password

To have your password reset, enter your email address below. We will then send an email containing a link reset your password.

Still having trouble?
If you're unable to reset your password, please call Customer Service at 1-866-936-8410 for assistance
Welcome back.
It's nice to see you again!
Start Shopping