
Crespine Gel Composition, Ingredients and Dosage Summary
What is Crespine Gel Plus?
Crespine Gel Plus is a single-use, intraarticular injection that can be used to help treat symptoms of osteoarthritis. As people get older, cartilage and the fluid within our joints, known as synovial fluid, becomes scarcer. This has an adverse effect on the joints and can cause issues such as pain and reduce mobility because there is less lubrication, leading to more friction between the bones. Crespine Gel Plus is formulated for injection into the knee and hip, and any other joints that are affected by osteoarthritis. Officially, Crespine Gel Plus is indicated as a replacement for synovial fluid in human joints and as a viscoelastic supplement, which means it is a supplement that is both viscous and elastic. Doctors will use Crespine Gel Plus to help patients who experience symptoms of osteoarthritis such as poor joint function and pain. It can be used when other treatments such as supplements or traditional drugs are not effective, and can help delay the need for knee or hip replacements. Â Â Â
Gel composition
Crespine Gel Plus is made of a combination of crosslinked and non-crosslinked sodium hyaluronate of non-animal origin. Sodium hyaluronate is the salt form of hyaluronic acid, which is a substance native to the human body that is found primarily in the skin and connective tissue. Hyaluronic acid is incredibly hydrating and is able to hold onto 1,000 times its own weight in moisture; therefore, it helps provide lubrication within joints. Sodium hyaluronate has a much smaller molecular weight than hyaluronic acid, which makes it more penetrative. Though sodium hyaluronate is a natural substance, the sodium hyaluronate in Crespine Gel Plus is of non-animal origin, which means it is created in a lab and is very pure.
Ingredients discussed
- Sodium hyaluronate 1mg: Sodium hyaluronate has a very similar composition as the fluid that surrounds the joints in our bodies. Because of this, and its incredible hydrating abilities, it is very effective at reducing pain and stiffness in joints such as the knee and hips. It is able to both lubricate the joint and absorb the shock caused by the repetitive and frequent movement involved in everyday life. It is a naturally occurring substance, which means it is metabolized by the body after injection, making it a temporary treatment ingredient.
- Sodium hyaluronate, cross-linked 14mg: Sodium hyaluronate in its natural form is non-crosslinked, and while it is still great for adding lubrication, it is quite flexible and does not stay put as well as crosslinked sodium hyaluronate. Crosslinked sodium hyaluronate also breaks down easier. Scientists are able to make sodium hyaluronate by crosslinking the substance, which essentially means that the molecules are linked together. This process makes the gel firmer and more durable, making it stay put in the injection are more easily. Crosslinking also makes the sodium hyaluronate more water absorbent and longer lasting.Â
- Prilocaine hydrochloride 3mg: Prilocaine hydrochloride is chemically related to another popular anesthetic, lidocaine. Prilocaine hydrochloride is including in the formulation of Crespine Gel Plus to provide a numbing effect in the area of injection, making the treatment procedure much more comfortable for the patient.
Dosage
Recommended dose
Crespine Gel Plus comes in a single-use, 2ml syringe that should not be disposed of after use. The dosage required during one treatment will depend on your symptoms and the severity of your osteoarthritis. It is important to discuss your medical history with your physician, including allergies, existing health conditions, and a current list of medications and supplements you are taking so that they can determine the proper dosage.
Missing a dose
As the ingredients in Crespine Gel Plus are biodegradable, that means patients will have to return for follow up treatments once the effects wear off. If you have missed a follow up treatment or dose, reschedule your appointment as quickly as possible. If it is close enough to your following treatment when you realize you’ve missed a dose, then simply wait for the following treatment appointment.
Overdosing
The results of treatment should last from six to twelve months, so treatments should only occur once or twice a year. Be sure to tell your physician the last time you received sodium hyaluronate injections to ensure treatments do not occur too closely together.
-
28 JanuaryBy: Medical Professional ContributorRhinoplasty, or nose shape alteration, is the third most requested ae ... Read more
-
20 FebruaryBy: Medical Professional ContributorTreating and Rejuvenating Lips The lips can be one of the prominent ... Read more
-
04 JanuaryBy: Medical Professional ContributorEmla is used medically by doctors and nurses to prevent pain and disco ... Read more
-
04 JanuaryBy: Medical Professional ContributorWhat are nasolabial folds? Nasolabial folds, also referred to as &ldq ... Read more
-
04 JanuaryBy: Medical Professional ContributorDefinition The Tyndall Effect is the formation of a bluish color at t ... Read more
-
04 JanuaryBy: Medical Professional ContributorDefinition Lidocaine is a local anesthetic that comes in a variety of ... Read more
-
04 JanuaryBy: Medical Professional ContributorJuvederm and Esthelis are brands of hyaluronic acid dermal fillers tha ... Read more
-
04 JanuaryBy: Medical Professional ContributorThick skin folds, loss of subcutaneous fat volume, and sunken cheeks a ... Read more
-
03 JanuaryBy: Medical Professional ContributorDysport is an injectable preparation of botulinum toxin type A. Botuli ... Read more
-
03 JanuaryBy: Medical Professional ContributorBelotero and Juvederm are two famous brands of hyaluronic acid cosmeti ... Read more
-
03 JanuaryBy: Medical Professional ContributorSimilarities Between Juvederm Fillers and Prevelle Silk Juvederm fill ... Read more
-
03 JanuaryBy: Medical Professional ContributorJuvederm is a brand of premier HA-based aesthetic fillers that are man ... Read more
-
03 JanuaryBy: Medical Professional ContributorDermal filler treatment for lips Dermal fillers are a great treatment ... Read more
-
03 JanuaryBy: Medical Professional ContributorHow can Juvederm and Radiesse be used for cheek augmentation? Juveder ... Read more
-
18 DecemberBy: Medical Professional ContributorThe aging process of the perioral area Chronological aging strikes us ... Read more
-
17 DecemberBy: Community AuthorThe generic name of this medication is follicle stimulating hormone. T ... Read more
-
14 DecemberBy: Community AuthorPresentation/Quantity Latisse ophthalmic solution is packaged in a 5m ... Read more
-
22 NovemberBy: Medical Professional ContributorHow do dermal fillers treat marionette lines? As the body ages, it sl ... Read more
-
21 NovemberBy: Medical Professional ContributorSkin peeling is not a foreign or modern invention in the beauty indus ... Read more
-
22 OctoberBy: Medical Professional ContributorCheap, accessible, and highly effective aesthetic procedures are in h ... Read more
-
17 OctoberBy: Medical Professional ContributorPreviously, the answer to nose augmentation or resculpting the nose w ... Read more
-
16 OctoberBy: Medical Professional ContributorJuvederm is dermal filler brand with a huge variety of formulas. Each ... Read more
-
12 OctoberBy: Medical Professional ContributorSculptra vs Juvederm may seem similar in terms of their indications o ... Read more
-
11 OctoberBy: Medical Professional ContributorThroughout the years, researchers have found a way to replenish the h ... Read more
-
10 OctoberBy: Medical Professional ContributorJuvederm is a premium collection of hyaluronic acid-based dermal fill ... Read more
-
09 OctoberBy: Medical Professional ContributorJuvederm, a top brand of hyaluronic acid-based filers, uses the cross ... Read more
-
05 OctoberBy: Medical Professional ContributorBelotero and Juvederm are two famous brands of hyaluronic acid cosmet ... Read more
-
04 OctoberBy: Medical Professional ContributorCosmetic fillers are biocompatible implants that aim to improve the b ... Read more
-
03 OctoberBy: Medical Professional ContributorJuvederm is one of the best-selling hyaluronic acid filler brands in ... Read more
-
-
02 OctoberBy: Medical Professional ContributorJuvederm is hyaluronic acid-based dermal filler brand that is manufac ... Read more
-
01 OctoberBy: Medical Professional ContributorAging affects both the face and the hands. With constant exposure to t ... Read more
-
28 SeptemberBy: Medical Professional ContributorAdults who are seeking to revive their youthful skin can be spoilt fo ... Read more
-
26 SeptemberBy: Medical Professional ContributorAre Orthovisc and Supartz made from the same ingredients? Supartz is ... Read more
-
27 SeptemberBy: Medical Professional ContributorLip injections are a delicate art. While some people only want minor ... Read more
-
25 SeptemberBy: Medical Professional ContributorLip correction involves more than just making it appear plumper. Thin ... Read more
-
24 SeptemberBy: Medical Professional ContributorScarring is a type of marked imperfection on the skin that comes in v ... Read more
-
21 SeptemberBy: Medical Professional ContributorDermal fillers are the closest thing to modern magic in the field of ... Read more
-
19 SeptemberBy: Medical Professional ContributorBoth Synvisc and Synvisc One are made of hylan A and hylan B, both of ... Read more
-
20 SeptemberBy: Medical Professional ContributorIf physical therapy and medication fail, a doctor might suggest visco ... Read more
-
17 SeptemberBy: Medical Professional ContributorOsteoarthritis is a form of arthritis that commonly attacks the knee ... Read more
-
14 SeptemberBy: Medical Professional ContributorIn the past decade, we have observed a surge of innovative and novel ... Read more
-
12 SeptemberBy: Medical Professional ContributorWhy do under eye bags appear? The area under the eyes is just as vul ... Read more
-
10 SeptemberBy: Medical Professional ContributorThe majority of the dermal fillers available in the aesthetics indust ... Read more
-
06 SeptemberBy: Medical Professional ContributorThe majority of the dermal fillers available in the aesthetics indust ... Read more
-
06 SeptemberBy: Medical Professional ContributorCosmetic fillers are solutions and implants that effectively improve ... Read more
-
04 SeptemberBy: Medical Professional ContributorOne of the key features of a person's appearance is the lips. When it ... Read more
-
03 SeptemberBy: Medical Professional ContributorThe chin defines the shape and sculpture of the face. Chin remodeling ... Read more
-
31 AugustBy: Medical Professional ContributorOne of the noticeable hallmarks of aging is sunken cheeks. Also known ... Read more
-
30 AugustBy: Medical Professional ContributorWhen an individual laughs or smiles, prominent lines and wrinkles app ... Read more
-
29 AugustBy: Medical Professional ContributorMarionette lines are the creases or wrinkles that run from the corner ... Read more
-
18 SeptemberBy: Medical Professional ContributorLaugh lines, sometimes known as smile lines, are creases or wrinkles ... Read more
-
07 SeptemberBy: Medical Professional ContributorTear troughs are delicate areas located under the eye—specifically ... Read more
-
24 AugustBy: Medical Professional ContributorRefresh Your Look with Restylane for Nasolabial Folds One of the sign ... Read more
-
23 AugustBy: Medical Professional ContributorHow to Assess the Lips for Lip Augmentation The ideal lips can be ch ... Read more
-
22 AugustBy: Medical Professional ContributorGet Rid of Under-Eye Bags with Restylane The presence of dark circl ... Read more
-
21 AugustBy: Medical Professional ContributorReduction of Forehead Lines with Restylane The forehead plays a rol ... Read more
-
20 AugustBy: Medical Professional ContributorContouring the Chin with Restylane The chin is a prominent area of th ... Read more
-
17 AugustBy: Medical Professional ContributorRadiesse: the resurgence dermal filler Radiesse is a sterile, cohesiv ... Read more
-
16 AugustBy: Medical Professional ContributorPeriocular dermatochalasis is the term for eye bags and excessive loo ... Read more
-
15 AugustBy: Medical Professional ContributorAs a major concern for many individuals, tear trough deformity has be ... Read more
-
14 AugustBy: Medical Professional ContributorIn the last decade, the industry has turned its focus to cosmetic ... Read more
-
13 AugustBy: Medical Professional ContributorAcne scarring is a phenomenon that can greatly affect the skin of man ... Read more
-
10 AugustBy: Medical Professional ContributorAcne Scars are a major concern when it comes to keeping smooth, heal ... Read more
-
09 AugustBy: Medical Professional ContributorWhat are the types of wrinkles formed on the forehead? The forehead ... Read more
-
08 AugustBy: Medical Professional ContributorMarionette lines are one of the visible signs of aging. These wrinkle ... Read more
-
07 AugustBy: Medical Professional ContributorA thread lift is a minimally-invasive procedure for facial rejuvenati ... Read more
-
03 AugustBy: Medical Professional ContributorWhat are Anal Fissures? An anal fissure is a tear in the thin tissue ... Read more
-
02 AugustBy: Medical Professional ContributorNasolabial folds are a distinct marker of aging. The folds appear fro ... Read more
-
31 JulyBy: Medical Professional ContributorThe majority of American couples have reported that penis width, not ... Read more
-
27 JulyBy: Medical Community MemberWhat is Hyaluronic Acid? Also known as hyaluronan, hyaluronic acid (H ... Read more
-
26 JulyBy: Medical Community MemberPermanent makeup, or cosmetic tattoo, is an extremely popular cosmeti ... Read more
-
20 JulyBy: Medical Community MemberRecently, butt lifts have become a common request in clinics across t ... Read more
-
25 JulyBy: Medical Community MemberBags or sagging in the under-eye area can give any patient a fatigued ... Read more
-
24 JulyBy: Medical Community MemberAesthetic physicians, beauticians, and practitioners have a large rol ... Read more
-
06 JulyBy: Medical CommunitySince the time of the ancient Egyptians, alabaster, animal oils, salt ... Read more
-
23 JulyBy: Medical Community MemberChemical peel treatments are used to treat skin conditions and reduce ... Read more
-
12 JulyBy: Medical Community MemberFrequent trips to the toilet, leakage, and wetting accidents are inci ... Read more
-
19 JulyBy: Medical Community MemberEven with strict strenuous physical training and healthy eating, stubb ... Read more
-
11 JulyBy: Medical Community MemberSweating is one of the most visible physiological reactions to our en ... Read more
-
17 JulyBy: Medical Community MemberThe face is often the first thing that comes to mind when we think of ... Read more
-
09 JulyBy: Medical CommunityDermal fillers vs botulinum toxins Nowadays, dermal fillers are join ... Read more
-
18 JulyBy: Medical CommunityThe Effects of Dermal Fillers on Weight LossCan patient lose dermal f ... Read more
-
10 JulyBy: Medical CommunityA nonsurgical nose job is an alternative option for individuals who d ... Read more
-
16 JulyBy: Medical Community MemberMany people would love to maintain the round and plump cheeks they ha ... Read more
-
13 JulyBy: Medical Community MemberIn the beauty industry, lips are often highlighted to be the most ess ... Read more
-
05 JulyBy: Medical Community MemberOne of the most vexing problems dealt with in cosmetic surgery is acn ... Read more
-
04 JulyBy: Medical Community MemberThe rise of Insta-worthy, Kylie Jenner-esque facial aesthetics has in ... Read more
-
03 JulyBy: Medical Community MemberRound, dewy, and plump cheeks can make any patient appear younger. Un ... Read more
-
28 JuneBy: Medical Community MemberWith the passage of time, the visible signs of aging, such as the loo ... Read more
-
26 JuneBy: Medical CommunityA liquid facelift is a safe, non-surgical cosmetic procedure that is ... Read more
-
22 JuneBy: Medical Community MemberUsing Juvederm for Nasolabial Folds: How Much is Needed? Nasolabial f ... Read more
-
21 JuneBy: Medical Community MemberTreating Stubborn Nasolabial Folds Nasolabial folds are natural inden ... Read more
-
20 JuneBy: Medical Community MemberThe skin plays an important role in a person’s appearance. As s ... Read more
-
19 JuneBy: Medical Community MemberMesotherapy makes use of a variety of substances that are injected ... Read more
-
18 JuneBy: Medical Community MemberIn the cosmetics industry, there has been a recent rise in demand for ... Read more
-
13 JuneBy: Medical Community MemberFor patients looking to reduce wrinkles, a variety of cosmetic treatm ... Read more
-
12 JuneBy: Medical Community MemberWhat to Expect from a Dermal Filler Procedure Dermal fillers are inje ... Read more
-
11 JuneBy: Medical Community MemberBotox for Migraine Headaches Botox is a neurotoxin that sourced from ... Read more
-
08 JuneBy: Medical Community MemberShould I Get Dermal Fillers? Dermal fillers have definite cosmetic be ... Read more
-
07 JuneBy: Medical Community MemberWhat is hyaluronic acid? Hyaluronic acid (HA) is naturally found in ... Read more
-
06 JuneBy: Medical Community MemberFacial wrinkles are creases, folds, or ridges that appear on the skin ... Read more
-
31 MayBy: Medical Community MemberCervical dystonia (CD) is an excruciating neurological condition invo ... Read more
-
04 JuneBy: Medical CommunityScars result from the skin’s natural repairing process. Dermal ... Read more
-
05 JuneBy: Medical Community MemberDermal fillers are non-invasive cosmetic treatments. During these pro ... Read more
-
01 JuneBy: Medical Community MemberChemical peels are an effective way to improve the skin’s appea ... Read more
-
30 MayBy: Medical CommunityType A Type A is produced by a bacterium called Clostridium botulinum ... Read more
-
29 MayBy: Medical Community MemberDermal fillers are a non-surgical method of facial rejuvenation and s ... Read more
-
24 MayBy: Medical Community1.   What is Botox used for? Botox has been proven to have both c ... Read more
-
24 MayBy: Medical Community MemberExperienced doctors know that patients need tailored treatment plans. ... Read more
-
27 JuneBy: Medical CommunityWhat you need to know about hyaluronic acid Hyaluronic acid (HA) is a ... Read more
-
29 JuneBy: Medical CommunityWhat are the effects of silicone injections? Liquid injectable silico ... Read more
-
10 AprilBy: Medical CommunityShould You Use Hyaluronic Acid? Hyaluronic acid is a carbohydrate th ... Read more
-
09 AprilBy: Medical CommunityEffective Ways to Reverse Signs of Aging Aging is an inevitable part ... Read more
-
08 AprilBy: Medical CommunityPurchase Botox from Trusted Sites Only Botox is an important tool for ... Read more
-
07 AprilBy: Medical CommunityHow do I know when I should use hyaluronic acid? HA hydrates the skin ... Read more
-
06 AprilBy: Medical Community MemberHyaluronic acid (HA) is an important natural substance found in severa ... Read more
-
23 AprilBy: Medical Community MemberEven the most diligent of health-care and spa workers face drug storag ... Read more
-
05 AprilBy: Medical CommunityThe most popular dermal fillers are Juvederm, Restylane, Belotero, ... Read more
-
01 AprilBy: Medical CommunityWhat you need to know about hyaluronic acid Hyaluronic acid ... Read more
-
03 AprilBy: Medical CommunityHow long a dermal filler lasts depends on its composition and the ar ... Read more
-
02 AprilBy: Medical CommunityAdvances in technology have provided cosmetic and surgical p ... Read more
-
04 AprilBy: Medical CommunityBotox should not be confused with the conditioning treatment being ... Read more
-
27 MarchBy: Jennifer JonesThey say the camera adds ten pounds, but it does not do your nose any ... Read more
-
13 FebruaryBy: Jennifer JonesWith the expanding uses of Botox in medicine, including migraines, the ... Read more
-
24 JanuaryBy: Jennifer JonesIn addition to regular Botox and Juvederm injections, many women swear ... Read more
-
21 DecemberBy: Jennifer JonesDumbo. Bat ears. Mr. Spock. Kids can be cruel, and children who gre ... Read more
-
22 OctoberBy: Jennifer JonesOne of the most common requests at medical spas is for fat reduction. ... Read more
-
01 DecemberBy: Jennifer JonesIt is no secret standards of beauty are changing. Pale skin was once t ... Read more
-
27 SeptemberBy: Jennifer JonesEven knowing smoking is bad for their health, many people continue to ... Read more
-
12 DecemberBy: Jennifer JonesEveryone knows Botox treats wrinkles of course. Chances are, these inj ... Read more
-
26 JulyBy: Jennifer JonesYou may think melasma is easy to detect. After all, you can clearly se ... Read more
-
22 JuneBy: Jennifer JonesMenopause brings many changes, thus the name "change of life". It mean ... Read more
-
26 MayBy: Jennifer JonesThere are many reasons people choose cosmetic surgery, including fight ... Read more
-
18 AprilBy: Jennifer JonesIf there is one area of the body you could blame most for giving cosme ... Read more
-
23 MarchBy: Jennifer JonesAs plastic surgery trends change over time, it is vital to keep up wit ... Read more
-
28 FebruaryBy: Jennifer JonesNearly all species, from bacteria to mammals, have hyaluronic acid in ... Read more
-
03 JanuaryBy: Jennifer JonesSomewhere between invasive procedures like surgical facelifts and the ... Read more
-
24 JanuaryBy: Jennifer JonesExercise can seem daunting, especially for older adults with mobility ... Read more
-
03 JanuaryBy: Jennifer JonesIn the month of January, try the new SILHOUETTE SOFT® thread lift ... Read more
-
05 DecemberBy: Jennifer JonesRefer a colleague to Medical Spa RX, and when they set up a new accoun ... Read more
-
01 DecemberBy: Jennifer Jones9 Ways to Fight Cellulite If you hate cellulite, you are not alone. B ... Read more
-
04 NovemberBy: Jennifer JonesSave on JUVÉDERM®! In the month of November only, when you ... Read more
-
04 NovemberBy: Jennifer JonesThere was a time when the typical cosmetic surgery patient was a woman ... Read more
-
13 SeptemberBy:The outdated Medicare payment system needs to offer more options for p ... Read more
-
Disclaimer: The contents of this article are for informational purposes only and must not be considered as medical advice. We, MedicalSparx.com do not agree, endorse, or approve opinions expressed by authors of our medical community. Articles are not reviewed for accuracy by MedicalSparx.com. You should always consult your doctor when seeking medical advice.