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AOD9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone and developed for research into metabolic regulation. Research suggests that it may influence lipid metabolism and fat oxidation processes, primarily through pathways involved in lipolysis and energy utilization without directly stimulating growth hormone or IGF-1 activity.

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General info
Brand

NOVERA COMPOUNDS

Strength

3mg

CAS

221231-10-3

Chemical Formula

C₇₈H₁₂₃N₂₃O₂₃S₂

Molecular weight

1815.10 g/mol

Peptide Sequence

Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-OH

Synonyms

AOD-9604, AOD 9604

Storage

Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.

Disclaimer: Sold as a research-grade lyophilized peptide in dry powder form. Requires reconstitution under controlled laboratory conditions. Reconstitution agents are not included.

For Research Use Only (RUO): Not for human or animal use, consumption, injection, or application. Not for diagnostic, therapeutic, or clinical purposes.

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Why Novera Compounds?

Advanced synthesis techniques ensure high structural fidelity and ≥99% purity.

Independent laboratories confirm identity, purity, and batch consistency.

Designed for reproducible laboratory and analytical applications.

Products meet Research Use Only (RUO) standards and relevant laboratory regulations.

Certificates of Analysis and quality verification reports provided for every lot.

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AOD 9604 — About This Product

AOD 9604 peptide is a synthetic fragment derived from the C-terminal region (amino acids 177–191) of human growth hormone (hGH). It retains the fat-metabolizing properties of growth hormone but excludes its growth-promoting effects. This peptide has a molecular weight of approximately 1,817 Da and is supplied as a lyophilized powder in a 5 mg vial with ≥98% purity. It is primarily used in research focused on fat metabolism, lipid oxidation, and tissue recovery.

AOD 9604 — Key Features and Benefits

  • High-Purity Peptide Fragment: ≥98% purity, derived from the lipolytic region of human growth hormone.
  • 5 mg Vial: Supplied in a 5 mg vial, ideal for laboratory research.
  • Metabolic Studies: Investigated for its role in lipid metabolism, fat oxidation, and energy expenditure.
  • Tissue Repair: Explored for potential effects on tissue repair and cartilage health.
  • Stable Formulation: Maintains chemical stability in lyophilized form; reconstitution recommended with sterile, pyrogen-free solvent.
  • Long-Term Storage: Suitable for long-term storage under controlled conditions.
  • Manufactured Under GMP-like Conditions: Produced to support laboratory reliability and reproducible research.

AOD 9604 — Mechanism & Research Applications

AOD 9604 peptide has been studied for its ability to stimulate fat metabolism through beta-3 adrenergic receptor (β3-AR) activation in adipose tissue, independent of growth hormone receptor signaling. Current research is focused on its effects on lipid metabolism, fat oxidation, and energy expenditure. It is also being investigated for tissue repair and cartilage health, though these applications are still in preclinical stages.

AOD 9604 — Dosing & Observed Effects in Research

In clinical trials, oral AOD 9604 doses ranged from 0.25–1 mg daily, with a 12-week study showing 1 mg daily resulted in an average weight loss of 2.6 kg compared to 0.8 kg for placebo. 

In animal studies, AOD 9604 has shown a 23–216% increase in fat oxidation and >50% reduction in adipose tissue. These effects were observed under controlled research conditions and are not applicable to human use.

AOD 9604 — Storage, Safety & References

Store AOD 9604 peptide lyophilized at –20°C or colder. For short-term use, room temperature storage (15–25°C) is acceptable. After reconstitution, store at 2–8°C and use within 5–7 days. Avoid repeated freeze-thaw cycles.

  • Use sterile technique and protective equipment when handling
  • Dispose of unused material according to local regulations

References

https://www.jofem.org/index.php/jofem/article/view/157/194

https://academic.oup.com/endo/article-abstract/142/12/5182/2988749

https://pubmed.ncbi.nlm.nih.gov/11673763

https://pubmed.ncbi.nlm.nih.gov/26275694

Compliance Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use.