CJC-1295 – No DAC (10mg) About This Product
The CJC No DAC peptide is a synthetic 29-amino-acid analog of growth hormone–releasing hormone (GHRH), also referred to as Modified GRF (1-29). Laboratories that buy or order CJC No DAC peptide materials reference this compound for controlled laboratory research examining the behavior of short-acting GHRH analogs and growth-hormone–axis signaling under experimental conditions.
Unlike DAC-modified variants, this peptide does not include a Drug Affinity Complex, resulting in a shorter duration of activity in research models. Several targeted amino-acid substitutions improve resistance to enzymatic degradation while maintaining structural compatibility with GHRH receptors. In laboratory settings, the peptide has been used as a research tool to evaluate endogenous growth hormone signaling patterns.
Product Specifications
- Molecular weight: 3367.9 g/mol
- Molecular formula: C₁₅₂H₂₅₂N₄₄O₄₂
- CAS numbers: 863288-34-0, 446036-97-1
- Form: Lyophilized powder
CJC-1295 – No DAC (10mg) Key Features and Benefits
- Chemical identity: 29-amino-acid GHRH analog (Modified GRF 1-29)
- Purity: Commonly produced at ≥95%, verified by HPLC
- Non-DAC format: Evaluated without long-acting carrier complexes
- Short activity window: Studied in experimental systems requiring transient peptide exposure
- Research focus: Examined in laboratory models assessing growth-hormone–axis signaling behavior
- Format: Supplied as a lyophilized powder suitable for controlled laboratory handling
For laboratory research use only.
CJC-1295 – No DAC (10mg) Mechanism & Research Applications
CJC-1295 without DAC has been examined in laboratory studies as a synthetic GHRH analog that interacts with pituitary cell models to evaluate endogenous growth-hormone release mechanisms. Rather than delivering exogenous hormones, the peptide is used in experimental systems to study upstream regulatory signaling under controlled conditions.
Research applications include:
- Growth-hormone–axis signaling studies in cell and animal models
- Temporal secretion pattern investigations examining pulse timing and recovery
- Metabolic regulation research models assessing downstream signaling markers
- Sleep-associated hormone research systems focused on experimental timing variables
All applications described reflect controlled laboratory research contexts and do not imply clinical or therapeutic use.
CJC-1295 – No DAC (10mg) Dosing & Observed Effects in Research
Research protocols using CJC-1295 without DAC vary by study design, species, and experimental objective. In laboratory settings, reported experimental dosing commonly ranges from microgram-level quantities administered once or multiple times daily, depending on the model used.
A 10 mg vial is typically reconstituted with bacteriostatic water to prepare a concentrated stock solution, which is then diluted to working concentrations appropriate for specific assays. Administration timing in research models is adjusted to evaluate short-term signaling behavior and recovery intervals.
Reported laboratory observations include transient changes in growth-hormone–related biomarkers, signal-transduction markers, and other assay-specific experimental readouts. These findings are derived exclusively from controlled research environments and do not establish safety, efficacy, or clinical relevance.
CJC-1295 – No DAC (10mg) Storage, Safety & References
- Store lyophilized vials at ≤ –20 °C; –80 °C recommended for long-term storage
- Keep vials sealed, dry, and protected from light
- Allow vials to equilibrate to room temperature before opening
- Reconstitute only with bacteriostatic water using sterile technique
- Store reconstituted solutions at 2–8 °C and use within 2–3 weeks
- Avoid repeated freeze–thaw cycles; aliquot when necessary
Handle materials in accordance with institutional laboratory biosafety protocols. Review the Certificate of Analysis (CoA) and Safety Data Sheet (SDS) prior to use.
References
https://academic.oup.com/jcem/article-abstract/91/3/799/2843281
https://www.fda.gov/media/183819/download
https://pubchem.ncbi.nlm.nih.gov/compound/CJC1295-Without-DAC
https://pubmed.ncbi.nlm.nih.gov/17018654
Compliance Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use.