PLINEST FAST Product Description
PLINEST FAST is a sterile injectable dermal biorevitalization treatment based on PN-HPT™ (Polynucleotides Highly Purified Technology). Developed by Mastelli, this advanced formulation is engineered for rapid skin regeneration, providing both immediate hydration and long-term improvement in skin structure.
Formulated with highly purified DNA polymers, PLINEST FAST is ideal for intensive treatments, skin priming, or as a preparatory procedure before other aesthetic interventions like laser, fillers, or microneedling. It is especially suitable for patients seeking quick recovery, brightening, and visible improvement in skin texture, with high biocompatibility and minimal downtime.
PLINEST FAST Key Features and Benefits
PLINEST FAST delivers fast-acting bio-revitalization to improve skin’s resilience and elasticity. It promotes natural cellular regeneration, enhances hydration, and restores skin tone and luminosity, making it ideal for patients with dull, tired, or dehydrated skin.
Key Benefits:
- Accelerated hydration and smoothing of the skin
- Boosts fibroblast activity and collagen production
- Prepares skin for other treatments with priming effect
- Enhances outcomes of aesthetic procedures
- Non-invasive, quick to apply, and virtually painless
- Visible improvement in skin firmness and elasticity
- Appropriate for younger and mature skin types
PLINEST FAST Composition
The PLINEST FAST formulation combines high molecular weight polynucleotides with a sterile, viscoelastic gel base, ensuring deep tissue integration and cellular activation.
Composition (per 2ml syringe):
- PN-HPT™ (Polynucleotides Highly Purified Technology): 15–20 mg (exact concentration may vary by protocol)
- Sterile, non-pyrogenic, viscoelastic gel
- No lidocaine, ensuring maximum tolerability even in sensitive areas
The DNA used in PN-HPT™ is derived from natural sources, fractionated and purified to produce a biologically active and safe formulation.
PLINEST FAST Intended Purpose / Indications
PLINEST FAST is intended for intensive revitalization treatments aimed at improving hydration, elasticity, and skin priming. It is suitable for both standalone therapy and in combination with other aesthetic modalities.
Primary Indications:
- Dull or dehydrated skin
- Early signs of aging and laxity
- Skin priming before laser, RF, fillers, or surgery
- Fine wrinkles and superficial lines
- Prevention of premature aging
It is particularly effective on the face, neck, and décolleté, with noticeable improvements even after a single cycle.
PLINEST FAST Injection and Treatment Areas
PLINEST FAST is designed for intradermal injection, targeting areas of low elasticity, rough texture, or fatigue-related dullness.
Recommended Treatment Areas:
- Full face
- Neck
- Décolleté
- Hands
- Forehead and cheek zones (pre-laser or filler)
Injection Depth: Intradermal
Technique: Micro-droplet or linear retrograde
Needle Size: Typically 30G ½ inch needle
Session Volume: 2ml per session (1 syringe)
PLINEST FAST Reconstitution and Preparation Guidelines
PLINEST FAST comes in a ready-to-use pre-filled syringe and requires no additional reconstitution or dilution. It is prepared under aseptic medical conditions.
Preparation Instructions:
- Allow product to reach room temperature before use
- Maintain sterility throughout handling
- Attach provided needle securely
- Prime syringe before injection
PLINEST FAST Administration and Dosage
PLINEST FAST is administered via intradermal injections by trained healthcare professionals. The protocol can be tailored based on patient age, skin condition, and intended outcome.
Standard Protocol:
- 1 session every 14–21 days
- Total of 3 sessions per treatment cycle
- Maintenance: 1 session every 2–3 months
Injection Techniques:
- Micro-droplets of 0.1–0.2 ml spaced evenly
- Linear retrograde injections along relaxed skin tension lines
Do not exceed 2 ml per session, unless advised by a physician.
PLINEST FAST Storage Instructions
To maintain the stability and sterility of PLINEST FAST, it should be stored under regulated conditions.
Storage Guidelines:
- Store at 2°C to 25°C
- Do not freeze
- Protect from light and heat
- Use before indicated expiry date
PLINEST FAST Contraindications
Though highly safe and biocompatible, PLINEST FAST is contraindicated in patients with specific medical risks or hypersensitivities.
Do Not Use In:
- Known allergy to polynucleotides
- Presence of infections or inflammation at injection site
- Pregnant or breastfeeding women
- Patients with autoimmune disorders
- Those on immunosuppressive therapy
PLINEST FAST Precautions and Warnings
When used correctly, PLINEST FAST has an excellent safety profile, but certain precautions must be followed to avoid complications.
Precautions:
- Avoid injecting into vascular structures
- Use only in clean, aseptic conditions
- Do not mix with other injectables in the same syringe
- Avoid aggressive massaging post-treatment
- Monitor for hypersensitivity in the first 24 hours
PLINEST FAST Post-Treatment Care
Aftercare is important to maximize outcomes and minimize side effects.
Post-Treatment Recommendations:
- Avoid makeup, UV exposure, and heat for 24–48 hours
- Do not apply pressure or massage treated areas
- Use cold compresses for swelling or redness
- Follow physician’s instructions for any additional skin care
PLINEST FAST Side Effects and Adverse Reactions
PLINEST FAST has undergone clinical safety evaluations and shows a low incidence of side effects, thanks to its high purification and bio-compatibility.
Common Side Effects:
- Mild redness, swelling, or itching
- Temporary bruising at injection sites
Rare Side Effects:
- Nodules or localized inflammation
- Infection (extremely rare)
- Allergic reaction (if patient is sensitized)
Patients are advised to report any unexpected or lasting symptoms.
PLINEST FAST Patient Eligibility
PLINEST FAST is ideal for a wide patient base, including young individuals for prevention and mature patients for correction and support.
Eligibility Guidelines:
- Patients aged 18 and above
- No active infections, chronic dermatologic diseases, or systemic illness
- Not currently pregnant or breastfeeding
- No history of severe allergic reactions or autoimmune disorders
PLINEST FAST Follow-Up and Maintenance
Ongoing treatments help maintain and amplify the effects of PLINEST FAST, especially for patients with aging skin or environmental skin damage.
Recommended Maintenance:
- Initial cycle: 3 sessions every 2–3 weeks
- Long-term: 1 session every 3 months
- Can be combined with laser, needling, peels, and fillers
PLINEST FAST Manufacturer and Regulatory Information
PLINEST FAST is manufactured by Mastelli Srl, a recognized innovator in aesthetic regenerative medicine. It meets the highest standards for quality and safety.
Manufacturer Information:
- Company: Mastelli Srl
- Location: Italy
- Medical Classification: CE-certified Class III medical device
- Packaging: 1 x 2ml pre-filled syringe with 2 x sterile 30G needles
- Traceability: Each syringe has a batch number and expiry date
PLINEST FAST FAQ
How soon will I see results?
Many patients see noticeable skin improvement after just one session, with full benefits developing over 2–4 weeks.
Is the treatment painful?
Pain is minimal. The use of fine 30G needles ensures a gentle injection experience.
Can it be used with other treatments?
Yes, PLINEST FAST is often used to prime the skin before other procedures like lasers or microneedling.
What age group is this best for?
It’s suitable for both preventive care in younger patients and restorative care in mature skin.
How long do results last?
Results can last 4–6 months, with longer effects seen when used regularly or in combination with other modalities.
