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    $69.00

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    Group Buy Price: $66

    brand:

    RENEFIL

    manufacturer:

    BMI Korea

    active substances:

    POLYDEOXYRIBONUCLEOTIDE, HA, LIDOCAINE

    INFORMATION

    RENEFIL DEEP PLUS is an advanced cross-linked hyaluronic acid (HA)-based dermal filler infused with polynucleotides (PN) and 0.3% lidocaine for patient comfort. As a hybrid filler, it is designed to simultaneously restore volume, improve skin texture, and promote biological regeneration through its innovative dual-action composition.

    Formulated with high-viscosity HA (20 mg/mL) and 1.875 mg/mL PN, RENEFIL DEEP PLUS delivers a balance of molding precision and low injection force, making it ideal for treating moderate to deep wrinkles and enhancing facial contours. It stands out as a next-generation filler that combines physical support with biological stimulation for long-lasting, natural-looking results.


    RENEFIL DEEP PLUS Key Features and Benefits

    This filler integrates the benefits of both HA and PN, offering volumization and regeneration in one solution. Its rheological and biological properties make it unique in the dermal filler market.

    Key features include:

    • Hydration and Brightening: PN improves hydration and skin radiance.
    • Fibroblast Stimulation: Promotes collagen production and tissue regeneration.
    • Long-Lasting Volume: Maintains its shape for up to 12 months or more.
    • Pain Relief: Contains 0.3% lidocaine to reduce injection discomfort.
    • Stable Structure: Resists deformation under skin pressure due to strong elasticity and cohesiveness.
    • Safe and Pure: Manufactured using 4L™ Technology for minimal BDDE and microbial contamination.

    RENEFIL DEEP PLUS Composition

    The hybrid formulation of RENEFIL DEEP PLUS includes high-quality ingredients optimized for effectiveness, safety, and injectability.

    Composition per 1 mL:

    • Cross-Linked Hyaluronic Acid (CL-HA): 20 mg
    • Sodium Polynucleotide (PN): 1.875 mg
    • Lidocaine Hydrochloride: 3 mg (0.3%)

    This balanced composition provides both structural volume and biological skin improvement, distinguishing it from conventional HA-only fillers.


    RENEFIL DEEP PLUS Intended Purpose / Indications

    RENEFIL DEEP PLUS is developed for treating moderate to deep facial wrinkles and volume loss in adult patients. It is particularly suitable for those seeking both aesthetic correction and skin regeneration.

    Indicated Uses:

    • Nasolabial folds
    • Cheek augmentation
    • Zygomatic enhancement
    • Chin projection
    • Nose reshaping
    • Mid-face contouring

    It also supports collagen synthesis and tissue repair, making it beneficial for improving skin firmness and fine lines over time.


    RENEFIL DEEP PLUS Injection and Treatment Areas

    The filler is designed for mid-to-deep dermal injection and can also be placed in the subcutaneous plane depending on the indication.

    Recommended Areas:

    • Cheeks
    • Chin
    • Nose
    • Nasolabial folds
    • Zygomatic zone

    Needle Size: 27G or 30G
    Particle Size: 600 μm
    Injection Depth: Mid to deep dermis or subcutaneous tissue


    RENEFIL DEEP PLUS Reconstitution and Preparation Guidelines

    RENEFIL DEEP PLUS comes in a ready-to-use format and does not require reconstitution. Preparation involves proper aseptic technique before administration.

    Preparation Guidelines:

    • Remove from refrigerated storage and allow to reach room temperature (not exceeding 25°C).
    • Use sterile gloves and tools during handling.
    • Attach the 27G or 30G needle provided with the prefilled syringe.
    • Ensure smooth flow by gently pressing the plunger before injecting.

    RENEFIL DEEP PLUS Administration and Dosage

    RENEFIL DEEP PLUS should only be administered by trained medical professionals with knowledge of facial anatomy and injection techniques.

    Injection Techniques:

    • Linear threading
    • Serial puncture
    • Fanning

    Typical Dosage per Area:

    • 0.5 mL to 1.5 mL depending on the treatment zone
    • Maximum of 2 mL per session recommended

    Massage gently after injection to ensure even distribution.


    RENEFIL DEEP PLUS Storage Instructions

    Proper storage ensures product efficacy and safety. The product should be kept under controlled temperature and light conditions.

    Storage Conditions:

    • Temperature: 2°C to 25°C
    • Avoid direct sunlight and freezing
    • Store in original packaging until use
    • Check expiry date before application

    RENEFIL DEEP PLUS Contraindications

    There are specific cases where RENEFIL DEEP PLUS should not be used, primarily due to potential adverse reactions or medical incompatibilities.

    Do NOT use in:

    • Patients with allergies to HA, PN, or lidocaine
    • Areas with infections or inflammation
    • Patients with autoimmune diseases
    • Pregnant or breastfeeding women
    • Individuals with coagulation disorders

    RENEFIL DEEP PLUS Precautions and Warnings

    While RENEFIL DEEP PLUS is well-tolerated, proper precautions are critical to minimize risks during and after administration.

    Important Precautions:

    • Avoid intravascular injection
    • Do not inject into eyelids or orbital area
    • Do not combine with other injectables in the same session
    • Monitor patients for hypersensitivity reactions

    Use caution when treating patients on anticoagulants or with a history of keloid formation.


    RENEFIL DEEP PLUS Post-Treatment Care

    Post-treatment care plays a crucial role in achieving optimal outcomes and minimizing side effects.

    Aftercare Instructions:

    • Avoid makeup for 12–24 hours
    • Avoid UV exposure, saunas, and extreme temperatures for 48 hours
    • Apply cold compresses if swelling occurs
    • Advise against massaging or pressing the treated area

    RENEFIL DEEP PLUS Side Effects and Adverse Reactions

    RENEFIL DEEP PLUS is manufactured under stringent standards to ensure minimal side effects, although minor and transient reactions may occur.

    Common Side Effects:

    • Redness or swelling at injection site
    • Bruising or tenderness
    • Temporary firmness or nodule formation

    Rare but Serious Reactions:

    • Infection
    • Hypersensitivity
    • Vascular occlusion

    Report any unexpected adverse effects to local regulatory authorities or the product distributor.


    RENEFIL DEEP PLUS Patient Eligibility

    The product is suitable for healthy adults seeking moderate to deep facial correction. A proper assessment must be done before treatment.

    Eligibility Criteria:

    • Age: 18 years and older
    • No active skin conditions or recent surgeries
    • Not currently pregnant or breastfeeding
    • No known hypersensitivity to filler ingredients

    RENEFIL DEEP PLUS Follow-Up and Maintenance

    To maintain optimal results, RENEFIL DEEP PLUS may require periodic reapplication based on the patient’s metabolic rate and skin condition.

    Follow-Up Protocol:

    • Initial result lasts up to 10–12 months
    • Repeat treatments recommended once annually
    • Evaluate patient at 3–6 months post-treatment for touch-ups if needed

    RENEFIL DEEP PLUS Manufacturer and Regulatory Information

    RENEFIL DEEP PLUS is manufactured by BMI Korea Co., Ltd., with rigorous compliance to ISO 13485 standards and CE marking under medical device regulation.

    Manufacturer Details:

    • Company: BMI Korea Co., Ltd.
    • Location: Jeju-do, South Korea
    • Certifications: CE (No. 2020-MDD/05-095), ISO 13485:2016
    • Patents: Registered in Korea, EU, USA, Russia, China, and Japan

    Each syringe is packaged with batch codes and an expiry date for traceability.


    RENEFIL DEEP PLUS FAQ

    Is RENEFIL DEEP PLUS safe for all skin types?
    Yes, it is suitable for all skin types when administered correctly.

    How long do results last?
    Typically 10–12 months, depending on the individual.

    Can it be combined with other treatments?
    Yes, but it should not be injected at the same time as other fillers.

    When can I return to normal activities?
    Most patients can resume normal activities after 24 hours, avoiding strenuous exercise or sun exposure.

    Is there any downtime?
    Minimal. Swelling or bruising may occur and subside within a few days.

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