Product Specifications
- Active Ingredient: Hyaluronic acid (cross-linked) 18.5mg/g; Lidocaine 0.3%
- Regulatory Status: CE-marked (EU); practitioners should verify current US FDA status and other applicable jurisdictions independently
- Molecular Type: Cross-linked hyaluronic acid (IPN-Like Technology™) with lidocaine; no mannitol
- Strength: 18.5mg/g HA | 0.3% Lidocaine
- Dosage Form: Injectable gel. Comes in a 1 × 1mL prefilled syringe (BI-FLEX® syringe system) + 2 × 30G ½ needles
- Manufacturer: Laboratories VIVACY
- Brand: STYLAGE®
- Country of Origin: France
- Storage Requirements: Store below 25°C; do not freeze; protect from direct sunlight
- Intended Use: Precise lip augmentation and perioral volume restoration. Only for licensed aesthetic professionals
- Packaging: Magenta/purple and white box. This is the updated visual identity under the BI-FLEX® rebrand
Who Is STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine Indicated For, and What Is the BI-FLEX® Rebrand?
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is specifically formulated for lip enhancement procedures requiring controlled volume placement and refined contouring. Common indications include lip augmentation, correction of volume loss, vermillion border definition, philtrum column enhancement, and improvement of selected perioral lines. Unlike fillers intended for deep wrinkle correction, this formulation focuses on precise shaping within the lips treatment area.
Formerly marketed as STYLAGE® SPECIAL LIPS (Bi-SOFT®), the product has been rebranded to BI-FLEX®, featuring an updated syringe system designed to improve ergonomics, injection precision, and practitioner control. The new magenta/purple and white packaging serves as a recognition cue for clinics re-ordering the product.
Patient Selection & Treatment Planning
To determine patient suitability, practitioners should assess the following clinical factors:
- Anatomical Assessment: Lip anatomy, tissue quality, and overall facial proportions.
- Patient Profile: Skin type, medical history, lifestyle factors, and specific treatment goals.
- Aesthetic Outcomes: The patient’s desired results and realistic expectations.
Product Performance & Longevity
- Variable Longevity: Treatment durability varies based on the injection area, individual metabolism, skin type, and lifestyle. Practitioners should consult the current Instructions for Use (IFU) for product-specific expectations.
- Clinical Advantages: Aesthetic professionals frequently favor STYLAGE® for lips due to its specialized formulation, IPN-Like Technology™, and the ergonomic BI-FLEX® precision syringe.
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is intended exclusively for licensed aesthetic medicine professionals trained in injectable procedures, facial anatomy, and complication management.
How Does STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine Work?
Following implantation, the cross-linked hyaluronic acid gel integrates into lip tissue and attracts water molecules, producing immediate volume enhancement, contour definition, and hydration at the injection site.
IPN-Like Technology™ comprises two interlocked hyaluronic acid polymer networks that enhance resistance to deformation from constant lip movement during speaking, eating, and facial expression. This helps maintain shape, projection, and definition while supporting natural facial expressions.
Unlike STYLAGE® M and STYLAGE® L, STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine does not contain mannitol, reflecting its specialized role in lip augmentation rather than broader facial volume restoration. The formulation also includes 0.3% lidocaine to improve patient comfort during injection in the sensitive lip treatment area.
If correction is required, the hyaluronic acid component can be reversed using hyaluronidase administered by trained professionals.
How Is STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine Administered, and What Are the Safety Considerations?
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine injection should only be performed by qualified aesthetic professionals familiar with lip anatomy, vascular safety protocols, and complication management. The product is typically administered within the lip body, vermillion border, and philtrum according to treatment objectives and practitioner preference. The BI-FLEX® syringe system supports controlled product delivery for detailed contouring and volume placement.
Lidocaine is incorporated into the gel at 0.3%; additional topical anesthetics may be considered when clinically appropriate. Following treatment, patients should avoid excessive sun exposure until visible inflammation subsides.
Common and Serious Side Effects
The most frequently reported side effects include:
- Swelling
- Redness
- Tenderness
- Bruising at the injection site
- Mild discomfort
These reactions generally resolve within a few days.
More serious complications, although rare, can include vascular occlusion, tissue ischemia, skin necrosis, and visual disturbances. Practitioners should follow accepted safety protocols and be prepared to manage vascular events promptly.
Treatment is contraindicated in patients with known hypersensitivity to hyaluronic acid or amide-type anesthetics and in those with active infection at the treatment site. Aseptic technique should always be maintained, and intravascular injection should be avoided. The practitioner should review the Full safety guidance within the manufacturer’s Instructions for Use (IFU).
What Is the Regulatory Status of STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine?
STYLAGE® SPECIAL LIPS BI-FLEX® with Lidocaine is manufactured in France by Laboratories VIVACY and carries CE marking for professional aesthetic use within applicable European jurisdictions. The product is intended exclusively for licensed medical professionals and qualified aesthetic practitioners. Current regulatory requirements differ by country and region, and practitioners should independently verify the product’s status, labeling requirements, and professional-use restrictions before procurement or administration.
Practitioners who wish to buy dermal fillers or buy STYLAGE® may contact Medical Spa Rx’s professional support team for sourcing information and documentation support. Practitioners evaluating buy STYLAGE® SPECIAL LIPS BI-FLEX® wholesale options should confirm that suppliers comply with applicable storage, transport, and regulatory standards. When buying online, practitioners should ensure that products originate from legitimate, properly authorized sources. Regulatory information is current as of mid 2026; always confirm local regulatory status before procurement or use.
For sourcing guidance, contact Medical Spa Rx’s professional support team.
