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$209 USD
The origin of this product is Europe
Manufacturer Galderma
Active Substance(s) Hyaluronic acid, lidocaine
Strength 20mg/ml, 3mg/ml
Pack Size 1-1ml prefilled syringe
Other Known Names EMERVEL DEEP
Accessories Package insert, 2-27G 1/2” needles, 2 traceability labels
Add 5 more units to your cart and save $60.00.
Packs For each
1 - 5 $ 209.00 USD
6 - 10 $ 199.00 USD
11 - 20 $ 194.00 USD
21+ USD$ 189.00 USD 189
Group Buy $ 189.00 USD

How can I order RESTYLANE® DEFYNE™ for my medical spa?

RESTYLANE® DEFYNE™ uses hyaluronic acid to correct deep wrinkles and comes as an injectable gel. You can purchase RESTYLANE® DEFYNE™ online from or you can phone our friendly customer service associates to place your order. When you buy wholesale RESTYLANE® DEFYNE™ from Medical Spa RX, you can help your clients regain a more youthful look as you fill their deep wrinkles and skin folds.

Where can I use RESTYLANE® DEFYNE™ to correct skin imperfections?

You should inject RESTYLANE® DEFYNE™ into the deep dermis or upper subcutaneous layer, and you can use it in most areas that have deep wrinkles or facial folds. These could include the marionette lines, which run from the mouth to the chin and can give a frowning or puppet-like appearance, or the nasolabial folds, which run from the nose to the mouth and can give the face a harsh appearance. Lines like these may appear on younger clients, but often they become deeper and more severe with age. When you treat your clients with RESTYLANE® DEFYNE™, you can fill in these wrinkles and lines to give their skin a more smooth, more youthful appearance.

Why do some medical spas prefer using RESTYLANE® DEFYNE™ to treat wrinkles?

Often different densities of dermal fillers are created by using non-cross-linked, or free, hyaluronic acid to change their concentration. The problem with this is the free hyaluronic acid can absorb water much like a sponge, causing side effects like swelling. RESTYLANE® DEFYNE™ uses a different process to create a different firmness for each dermal filler. The manufacturers pass RESTYLANE® DEFYNE™ through a sieve, which sorts the cross-linked hyaluronic acid into different particle sizes. Each particle size is suitable for a different application, with RESTYLANE® DEFYNE™ having the second-highest particle size. This makes RESTYLANE® DEFYNE™ most suitable for treating deep wrinkles and lines. All the EMERVEL® products maintain the same concentration with no free hyaluronic acid to cause excess swelling.

When does RESTYLANE® DEFYNE™ degrade within the skin?

Hyaluronic acid normally breaks down quickly within the body, but RESTYLANE® DEFYNE™ is cross-linked. This cross-linked hyaluronic acid helps RESTYLANE® DEFYNE™ continue smoothing wrinkles for about six to nine months. Clinical trials showed that the results of an RESTYLANE® DEFYNE™ treatment can even last up to twelve months. When their wrinkles and skin folds do start to reappear, your clients can return to your medical spa for another RESTYLANE® DEFYNE™ injection treatment.

What RESTYLANE® DEFYNE™ side effects could my clients experience?

Although they usually resolve a few days later, RESTYLANE® DEFYNE™ injections could cause side effects like mild pain and tenderness, redness, itching, and swelling at the injection site. You should not use RESTYLANE® DEFYNE™ to treat your clients who are pregnant or breastfeeding or that have an autoimmune disorder, porphyria, severe allergies, or an allergy or sensitivity to hyaluronic acid, Lidocaine, or amide anesthetics. You should also not inject RESTYLANE® DEFYNE™ into areas of the body that already have a dermal filler, especially a permanent filler, or that have acute or chronic skin lesions.

Who can buy RESTYLANE® DEFYNE™ for their medical spa?

If you are a dermatologist, plastic surgeon, or other type of physician or medical practitioner, you can purchase RESTYLANE® DEFYNE™ for your medical spa. When you order wholesale RESTYLANE® DEFYNE™ from Medical Spa RX, you can help correct deep wrinkles and creases to give your clients more smooth, more youthful-looking skin.

More Information About RESTYLANE® DEFYNE™

View Restylane Products

View Cosmetic Fillers

Information about this product that is provided by is only summary, and does not cover all of the information about this product.

* Medical Spa RX offers only genuine RESTYLANE® DEFYNE™ that is manufactured by Q-Med/Galderma. All brands listed here including RESTYLANE® DEFYNE™ are the trademarks of their respective owners. Medical Spa RX is not operated by, supported by or affiliated with Q-Med/Galderma.

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