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A recent study published in the Journal of the American Academy of Dermatology found that nearly 90% of people develop wrinkles by their late 30s. Repeated muscle contractions cause wrinkles to etch into the skin over time, prompting many to seek facial rejuvenation and chase after a youthful appearance.

Xeomin offers a unique solution that addresses the root cause of wrinkles rather than merely masking their cosmetic appearance. This approach can lead to more natural-looking and longer-lasting results. Xeomin explicitly targets the underlying muscle activity that leads to wrinkle formation, helping preserve natural facial expressions while avoiding the stiffness sometimes associated with similar treatments.

This article discusses the early days after Xeomin treatment, addressing immediate concerns while promoting long-term skin health.

Key Takeaways

  • Xeomin starts to work in 3-7 days, with full effects showing in up to 30 days. It lasts about 12-16 weeks.
  • After treatment, expect redness, swelling, and discomfort at the injection spots. These side effects are usually short-lived.
  • Avoid heavy exercise and heat for the first 24 hours post-treatment to help manage side effects better.
  • Ice packs can ease swelling and pain in the treated areas shortly after getting Xeomin.
  • Follow-up visits with your doctor are essential to check progress, address concerns, and plan future treatments if needed.

What is Xeomin?

Xeomin is a treatment that reduces wrinkles and frown lines by relaxing facial muscles that cause lines when we frown or squint. Results start in about three to four days, with the best effects visible after a week or up to 30 days. The improvements from this treatment typically fade after 12–16 weeks. 

To keep results looking their best, staying out of strong sunlight for at least three days post-treatment and avoiding heavy exercise or heat for a day is good. Side effects like feeling flu-ish or weak muscles might pop up but are uncommon for everyone. Following your doctor’s instructions can help manage any discomfort.

Comparison to Other Botulinum Toxin Type A Injectables

Transitioning from an overview of Xeomin, let’s examine how it stands apart from other botulinum toxin type A injectables. This comparison highlights vital distinctions and similarities, offering valuable insights for medical professionals.

Active IngredientBotulinum toxin type ABotulinum toxin type ABotulinum toxin type A
Accessory ProteinsNonePresentPresent
Onset of Action3-7 days2-10 days2-4 days
Duration of Effect12-16 weeks12-16 weeksUp to 5 months
Post-Treatment CareAvoid exercise and heat exposure for 24 hours, no lying down for 4 hoursSimilar to XeominSimilar to Xeomin, with additional precautions in some cases
Unique ConsiderationsMinimal risk of antibody formation due to lack of accessory proteinsWidely recognized and researchedIt may spread slightly more, affecting a more extensive area
Visible Results3-7 days, full effects in up to 30 daysUsually within 72 hours, full effects within two weeksVisible improvement within a few days
Temporary Side EffectsFlu-like symptoms, swelling, rednessSimilarly, with the potential for headacheSimilar, plus the risk of eyelid drooping

The distinctive formulation of Xeomin sets it apart from its counterparts in the market. This absence reduces the body’s immune response, decreasing the likelihood of developing resistance. Each product, while based on the same active ingredient, presents specific considerations for use. 

How Does Xeomin Work?

This treatment stops nerves from telling muscles to contract, smoothing out the treated areas. Muscles injected with Xeomin botulinum toxin stop moving for a while, so frown lines and crow’s feet look better after treatment. This effect helps lessen unwanted facial expressions and wrinkles. 

Targeted Muscles and Areas of Treatment

Shifting from how Xeomin works, we now focus on its action areas. This treatment targets specific muscles to smooth wrinkles and fine lines. Doctors usually use it for the frown lines between the eyebrows, also known as glabellar lines. 

Xeomin injections can also improve areas like neck bands. The key is choosing the right spots to inject for each person’s unique needs. Many find it reliable for maintaining a youthful look without permanent changes.

Immediate Post-Treatment Effects

Right after Xeomin treatment, patients often see redness and swelling at the spots where they got their shots. Mild discomfort is also joint. These effects should not worry you too much—they are normal and do not last long. Usually, these symptoms start to get better after a few days.

  • Redness: Patients may experience redness at the injection site after receiving Xeomin treatment, a common side effect and nothing to worry about.
  • Swelling: Applying ice packs to the affected area can reduce swelling, which is a common side effect of Xeomin treatment.
  • Mild Discomfort: Patients may experience mild discomfort at the injection site after receiving Xeomin treatment. If they take over-the-counter pain relievers, this discomfort should quickly subside.

Duration and Intensity of Common Posttreatment Effects

Most people feel better within a few hours to days after getting Xeomin. Minor things like redness and swelling in the injection area are present daily. They usually last up to a couple of days. People might sometimes feel weak or have blurry vision, but this is rare and fades away quickly.

Expecting flu-like symptoms isn’t out of the ordinary, either. For most people, these experiences pass quickly, but they can vary depending on the individual’s body reactions. Staying out of the sun for 72 hours helps ensure you get the best results without the extra trouble.

Timeline for Visible Results

Wrinkles start to smooth out, giving the skin a fresher look. Full results can take up to a week or even 30 days. Everyone is different, so the timing can vary from one person to another. Xeomin starts working fast and keeps improving the skin’s appearance. 

The effects last about 3-4 months before they fade. During this period, actions like frowning become less prominent, leading to fewer visible lines and wrinkles on treated areas such as crow’s feet and forehead lines.

The timeline for full effects and optimal results varies for each person. Some may start seeing changes as soon as three days. The peak of these effects often hits around the one-month mark, when patients can see the optimal treatment outcome. 

Managing Discomfort and Side Effects

It’s common to have side effects after receiving Xeomin. Knowing how to manage them is crucial. Here are some essential post-treatment care tips to help you achieve optimal results.

  • To reduce swelling and discomfort, apply ice packs wrapped in cloth for 20 minutes on and 20 minutes off for the first 24 hours after treatment.
  • Avoid strenuous activities such as jogging and heavy household chores for 24 hours.
  • Keep the head elevated for at least 4 hours post-treatment to prevent Xeomin from spreading.
  • Avoid heat sources like saunas and hot showers or baths for 24 hours to minimize swelling.
  • Use over-the-counter pain relievers if needed, but avoid aspirin or ibuprofen to reduce the risk of bruising. Consult your doctor before taking any medication if you have any underlying health conditions.
  • Use mild, lukewarm water to wash the face gently without rubbing for a day. Avoid using any harsh soaps or scrubs on the treatment area.
  • Apply sunscreen if going outdoors within 72 hours to protect the treated area. 
  • Stay hydrated by drinking lots of water and rest if flu-like symptoms occur. 
  • Contact a healthcare provider immediately for severe side effects like muscle weakness or vision issues.

Importance of Follow-up Assessment

Follow-up assessments after Xeomin treatment are essential. They let doctors check your progress and ensure you’re happy with the results. During these visits, you can discuss any concerns or unexpected effects of the treatment. The doctor might adjust plans based on how you respond to Xeomin. 

It’s a chance to ensure everything is going well and discuss future treatments if needed. These appointments help catch rare side effects early, such as muscle weakness or vision issues.  Always share your feelings with your doctor to keep your recovery smooth and safe. Plus, it helps you plan when to schedule your next Xeomin session for lasting results.

Addressing Concerns and Assessing Treatment Outcomes

Doctors should always listen to their patients’ worries after they get Xeomin. Some may talk about muscle weakness, blurred vision, or drooping eyelids, which can start a few hours to weeks after treatment. Medical professionals must evaluate these outcomes properly.

They must decide whether these signs are typical side effects or something more serious. Follow-up meetings are vital moments to check how well the treatment works. Medical professionals can now assess whether the outcomes of a medical test align with the expected results. This time also allows them to give any needed advice on further care or treatments.

Post-Treatment Guidance and Reassurance

Managing patient expectations and addressing concerns are crucial after Xeomin’s treatment. Side effects such as redness, swelling, and temporary weakness usually subside within days. Educating patients on avoiding sun exposure and intense exercise can aid recovery.

Monitoring post-treatment changes, staying hydrated, and getting adequate rest can alleviate temporary discomfort. Open communication with healthcare providers ensures prompt attention to concerns. Advising patients to avoid intense exercise and lying down for four hours after treatment can achieve excellent results.

Guiding and reassuring patients about their Xeomin journey is critical. Results may vary for each individual, so setting realistic expectations is crucial. Sharing knowledge empowers patients, boosting confidence in the treatment process.


Xeomin treatment offers the potential for long-lasting, natural-looking results. Patients can approach their recovery confidently and optimistically by understanding what to expect during the first few days after Xeomin treatment and following post-treatment care instructions.

About: MedicalSpaRX is a one-stop shop for wholesale medical and cosmetic supplies. They offer a wide range of products, including dermal fillers, Botox, and skin care products, at competitive prices with fast shipping. Plus, they have a referral program that rewards you for introducing new customers.


1. Is Xeomin like Botox, and is it safe?

Yes, Xeomin functions similarly to Botox, targeting wrinkles such as crow’s feet, and Xeomin is FDA-approved, ensuring its safety.

2. How quickly does Xeomin start working?

Results from Xeomin injections may appear within 3-4 days, with optimal effects typically manifesting after approximately two weeks.

3. Where can I get Xeomin injections?

Xeomin injections are administered in various areas prone to wrinkles, including around the eyes and forehead, always by a trained professional.

4. What should I avoid doing after getting Xeomin?

Following Xeomin treatment, refrain from rubbing the injection site and engaging in strenuous exercise to allow the treatment to settle effectively.


Hefter H, Brauns R, Beyza Ürer, Rosenthal DI, Albrecht P. Effective long-term treatment with incobotulinumtoxin (Xeomin®) without neutralizing antibody induction: a monocentric, cross-sectional study. Journal of Neurology. 2020;267(5):1340-1347. doi:

Skin Care Category. Dr. Axe. Accessed April 9, 2024.

Xeomin vs. Botox: Uses, Efficacy, and Side Effects. Verywell Health.