Staying ahead is crucial for success. As medical professionals, your pursuit of perfection in enhancing beauty demands the best tools in your arsenal. Yes, we are talking about the most popular dermal fillers. In an industry where every, even the smallest, move is under heavy scrutiny, you must not settle for the average. You have to aim for the premium things only.

Looking back at the year 2023, we reveal the best-selling filler options offering top-notch results that go beyond expectations, attracting clients hungry for aesthetic excellence. Let’s together propel your practice to new heights!

This Year’s Best-Selling Dermal Fillers

  • Euflexxa
  • Fillmed M-HA 10
  • Restylane Volyme
  • Restylane Kysse
  • Hyalgan
  • Saypha Volume Plus
  • Juvederm Voluma
  • Nabota
  • Radiesse
  • Juvederm Ultra 4


It is not surprising that Euflexxa is at the very top of the most popular dermal fillers brand list. Made by Ferring Pharmaceuticals, a Swiss biopharmaceutical company, Euflexxa’s exceptional ability to address osteoarthritis-related pain makes it a standout solution.

We all know how many people struggle with this kind of problem and Euflexxa is a lifesaver for many of them because it promotes a good quality of life. Active components are sodium hyaluronate, sodium chloride, disodium hydrogen phosphate dodecahydrate, dihydrogen phosphate dehydrate, and water. So, the next time you see a patient with osteoarthritis, Euflexxa should be one of your first solutions.

Fillmed M-HA 10

Celebrated for its hydrating prowess, Fillmed M-HA 10 emerges as a versatile filler, adding a touch of rejuvenation to the skin. This exceptional product goes beyond surface-level hydration, with its unique composition ensuring optimal skin revitalization. Tone and elasticity improvements are easily noticeable.

If it’s not already, Fillmed M-HA 10 will be an invaluable addition to your toolkit, for providing clients with a radiant and refreshed complexion. Its transformative effects make it a go-to choice for delivering lasting results.

Restylane Volyme

Restylane Volume precision in adding volume to specific areas, coupled with long-lasting effects, caters to clients yearning for the youthful appearance they once had. As a soft tissue filler, it usually lasts from 6 to 12 months.

It contains lidocaine, which makes the injection process painless for patients. For some, it may seem insignificant, but for sensitive patients, it is the difference between doing the procedure or giving up the whole process. Another advantage is the very short duration of administration, usually less than half an hour.

Restylane Kysse

Restylane appears again on our list of the most popular dermal fillers in 2023.

Nasolabial folds, wrinkles, fine lines, and glabellar folds are among the most common reasons why patients come to your medspa or clinic, but nothing less common is loss of lip volume or general dissatisfaction with the look of the lips.

Restylane Kysse is the undisputed choice for natural-looking lip enhancement. Its smooth consistency allows you to create beautifully defined lips, setting new standards in lip augmentation.


Let’s talk about another important product for the treatment of orthopedic problems, especially knee pain. Hyalgan transcends conventional fillers, positioning itself as a leading solution for osteoarthritis-related pain.

Beyond its remarkable ability to alleviate discomfort, Hyalgan enhances joint function.

Main ingredient is shyaluronate, a natural fluid used for lubricating and cushioning knee joints. Anyone who has ever experienced knee pain knows how limiting it is, and knee pain as a result of osteoarthritis often leads to the abuse of painkillers, making the role of Hyalgan even more significant.

Saypha Volume Plus

We can single out Saypha Volume Plus as the most popular facial filler for its amazing ability to reduce facial folds and wrinkles while improving dermal volume. Not many products can restore facial volumization and achieve a naturally youthful appearance like this one.

It’s highly dense hyaluronic acid made with S.M.A.R.T. (Supreme Monophasic and Reticulated Technology) system, with added lidocaine for pain reduction during administration.

You can be 100% sure of the safety and purity of the product because it is made by CROMA-PHARMA, a company that sells products in over 100 countries and has numerous subsidiaries.

Juvederm Voluma

Voluma by the best-selling filler brand Juvederm has an exceptional ability to address age-related volume loss. Many patients talked about a transformative experience, helping them effectively combat the signs of aging and restoring a youthful and voluminous appearance to the face.

It is pure hyaluronic acid, with just 0.3% lidocaine hydrochloride, and 1ml of phosphate buffer. This clean composition guarantees results for both you and your patients because you know exactly what you are using.


Nabota, a refined botulinum toxin type A (Botox), operates with precision in targeting facial muscles. Its unique formulation allows practitioners to achieve a delicate balance – reducing the appearance of fine lines and wrinkles while preserving the natural expressiveness of the face.

The injections temporarily relax facial muscles, resulting in a visibly smoother complexion without resorting to invasive procedures.

One of the hallmarks of Nabota is its durability. Clients can enjoy the benefits of smoother skin for an extended period before considering additional treatments.


Merz Pharma Radiesse is known for its best-selling dermal filler. Radiesse, a calcium hydroxylapatite-based (CaHA) filler, takes center stage by not only providing immediate volume but also contributing to sustained skin revitalization over time. It can ignite collagen production and that is something that sets it apart. Immediate results are great, but long-term revitalization is even better.

Juvederm Ultra 4

Taking advantage of Juvederm Ultra 4 for targeting moderate to severe facial wrinkles and folds, it emerges as a reliable choice for practitioners aiming to deliver comprehensive facial rejuvenation. Its smooth consistency ensures a seamless integration, providing natural-looking results that stand the test of time.

It can address a wide spectrum of facial concerns, but many experts find Ultra 4 the best for sunken cheeks. Since sunken cheeks are the main concern of many women, so you will often use Ultra 4.

Choosing the Right Dermal Filler

Navigating the diverse landscape of dermal fillers demands a strategic and precise approach. That’s why we won’t leave you only with best-selling filler brands but we will give you tips to ensure you select the ideal dermal filler that aligns with client’s unique needs:

  • Client Consultation – Conduct a comprehensive consultation to understand the client’s goals, concerns, and medical history. Also, assess the specific facial areas that require treatment.
  • Desired Outcome – You must take into consideration whether the client wants volume enhancement or to address fine lines and wrinkles. This will have a decisive influence on the choice of one of the most popular fillers.
  • Area of Treatment – For lip augmentation, Restylane Kysse is a preferred choice for natural-looking, while for joint pain relief Hyalgan is a better option.
  • Longevity and Maintenance – Evaluate the longevity of the results required. Don’t forget to discuss post-procedure recovery and maintenance requirements with the client as well, ensuring alignment with their lifestyle.
  • Client Preferences – Check whether smooth texture, natural look, and feel, or something else is most important to the client.
  • Budget Considerations – Discuss budget constraints with the client and offer suitable options without compromising on quality or safety. Consider offering package deals for multiple sessions to improve client loyalty and satisfaction.
  • Risk and Side Effects – Provide detailed information on potential risks and side effects associated with each most popular filler, ensuring informed consent. Screen for allergies and sensitivities to prevent adverse reactions, choosing fillers with a lower risk profile when necessary.
  • Continuous Education and Product Updates – Stay up-to-date with the latest advancements in dermal fillers through continuous education and training. Regularly check for changes in formulations.
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Elevate Your Practice By Opting For The Bestsellers

In the fashion world, bestselling does not always mean the best or the highest quality. But when we talk about dermal fillers and similar products, bestsellers guarantee us fantastic results. Most popular dermal filler brands elevate client satisfaction, making them come back to you. So, we did homework for you and helped you navigate the ever-evolving field of medical aesthetics. Now, choosing the right dermal filler will be a walk in the park.