A 2024 systematic review emphasizes the regenerative power of polynucleotides (PDRN) in aesthetic medicine, showcasing their ability to stimulate fibroblast activity, boost hydration, and promote collagen synthesis. These DNA-derived molecules offer a promising solution for enhancing skin texture and resilience.
Building on this foundation, CROMA has launched PhilArt Products, injectable treatments formulated with high-purity polynucleotides. Unlike traditional volumizing treatments, PhilArt focuses on improving skin quality through subtle biostimulating effects. Suitable for areas such as the face, eyes, and scalp, these treatments appeal to patients seeking natural-looking, rejuvenated results.
In this article, we’ll break down the full range of PhilArt formulations, exploring their unique applications and how they support skin and tissue regeneration
Key Takeaways
- PhilArt products utilize high-purity polynucleotides (PNs) to stimulate skin regeneration, enhance hydration, and promote collagen synthesis, providing subtle, natural results for various skin concerns.
- For enhancing skin quality, PhilArt offers its Classic variant. It addresses dullness, fine lines, and loss of elasticity without altering facial volume, making it a trusted treatment for long-term skin rejuvenation.
- PhilArt EYE is specifically formulated for the delicate periorbital area, reducing fine lines, dark circles, and skin thinning while improving elasticity—administered in sessions spaced 2–3 weeks apart.
- When treating hair concerns, PhilArt HAIR can deliver scalp vitality and hair follicle regeneration. The treatment shows significant improvements in hair density and texture with 3–4 sessions and visible results in just a few weeks.
- PhilArt NEXT supports pre- and post-treatment care by enhancing skin resilience and hydration, and accelerating recovery after aesthetic procedures such as laser treatments or fillers.
- PhilArt offers non-invasive, natural-looking results for patients seeking enhanced skin health and hair vitality, supported by polynucleotide technology that promotes collagen production and improves overall skin quality.
- Regular sessions and personalized treatment plans are essential for achieving optimal results with PhilArt formulations.
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How CROMA PhilArt Stimulates Skin and Tissue Regeneration
CROMA PhilArt stimulates skin and tissue regeneration by utilizing high-purity polynucleotides (PNs) derived from salmon DNA. These potent biostimulators work to rejuvenate the skin’s extracellular matrix, enhance fibroblast activity, and boost collagen synthesis. Due to their hydrophilic nature, PNs help the skin retain moisture, leading to smoother, more hydrated skin. By improving elasticity, these molecules support the growth of new, healthy cells, which is key to enhancing overall skin quality.
PhilArt is distinct from traditional fillers because its products prioritize skin rejuvenation over volume addition. It’s an excellent choice for patients seeking subtle, natural-looking enhancements in skin health and resilience.
CROMA PhilArt Classic: Foundation for Skin Rejuvenation
CROMA PhilArt Classic is a foundational skin rejuvenation treatment that features non-crosslinked polynucleotides. It works by stimulating cell regeneration, improving hydration, and enhancing skin tone. Ideal for areas like the face, neck, and décolletage, this treatment addresses concerns such as dullness, fine lines, and early signs of skin elasticity loss.
Unlike traditional fillers, PhilArt Classic subtly improves skin quality without altering the facial contours. Patients seeking natural-looking enhancement can benefit the most from this variation. PhilArt Classic is well-tolerated with minimal side effects, making it a trusted choice for long-term biostimulation and improved skin resilience.
CROMA PhilArt EYE: Specialized Use in the Periorbital Area
CROMA PhilArt EYE is specifically formulated for the delicate periorbital area, targeting early signs of aging, including fine lines, dark circles, and skin thinning. This treatment uses a lower concentration of polynucleotides, ensuring safety while promoting regeneration in the sensitive skin around the eyes. Administered via micro-needles or cannulas, the treatment typically requires two to three sessions, spaced approximately 2–3 weeks apart, as per CROMA’s standard protocol.
PhilArt EYE is ideal for those looking for a refreshed, natural appearance, enhancing elasticity without adding volume. Adverse effects are uncommon and generally mild, making this treatment a gentle yet effective solution for revitalizing tired eyes.
CROMA PhilArt HAIR and NEXT: Expanding Into Scalp and Pre-Treatment Care
CROMA PhilArt HAIR and NEXT expand regenerative care beyond the face, offering targeted treatments for scalp vitality and pre-treatment support. PhilArt HAIR is designed to stimulate scalp health and enhance hair follicle vitality with polynucleotides. By improving blood circulation and supporting tissue regeneration, it is particularly effective for early-stage hair loss, including androgenetic alopecia. It also helps improve hair density, texture, and scalp condition.
Typically administered over 3–4 sessions, with visible results in just a few weeks, PhilArt HAIR provides long-lasting benefits for scalp health. PhilArt Hair before and after images have shown noticeable improvements in both hair quality and density, making it an ideal option for patients seeking non-invasive hair restoration.
On the other hand, PhilArt NEXT is designed as pre- or post-treatment support for aesthetic procedures, such as laser treatments or fillers. It helps maintain hydration and encourages cellular activity, accelerating healing and boosting skin resilience. It can be used alone or as part of customized regimens to extend treatment benefits and ensure overall skin wellness.
Conclusion
CROMA PhilArt products represent an innovative approach to skin and tissue regeneration, offering tailored solutions for the face, eyes, and scalp, and providing comprehensive support for aesthetic treatments. With polynucleotide technology at their core, these treatments enhance hydration, collagen production, and overall skin quality, without altering facial volume.
Whether seeking subtle rejuvenation, improved skin resilience, or enhanced hair vitality, PhilArt delivers science-backed results to meet a variety of patient needs. Choosing the right formulation ensures that your journey toward healthier, more natural-looking beauty is both effective and precise.
FAQs
1. What are polynucleotides, and are they safe?
Polynucleotides are DNA fragments derived from salmon that stimulate cell repair. They are biocompatible and safe for use.
2. How soon can I expect to see results after a PhilArt treatment?
Results usually appear after 2–3 weeks, with progressive improvements in hydration, texture, and skin tone.
3. How many sessions are needed for optimal results?
Most protocols recommend 3 sessions spaced a few weeks apart, depending on the product and treatment area.
4. Is there downtime after a PhilArt procedure?
Downtime is minimal. Patients may experience mild swelling or redness, which typically resolves within 24 to 48 hours.
5. Who is a good candidate for PhilArt treatments?
PhilArt is ideal for patients seeking natural rejuvenation without fillers, particularly those with early signs of aging.
6. Are PhilArt products suitable for all skin types?
Yes, PhilArt products are suitable for a wide range of skin types and tones, with minimal risk of adverse reactions.
References
Webb WR, Rahman E, Rao P, et al. Points to ponder on the role of polynucleotides in regenerative and aesthetic medicine: a systematic review. European Journal of Plastic Surgery. 2024;47(1). doi:10.1007/s00238-024-02209-x
Ruiz-Ojeda FJ, Plaza-Diaz J, Gil A. RNA analyses. In: Elsevier eBooks. ; 2019:41-48. doi:10.1016/b978-0-12-804572-5.00006-9
Croma-Pharma introduces its newest injectable polynucleotide, PhilArt. Aesthetic Medicine. Published April 8, 2023. https://aestheticmed.co.uk/croma-pharma-introduces-its-newest-injectable
