Skin-booster injections (HA-based “skin boosters” or biostimulators) have become essential in addressing signs of aging, offering hydration and enhancing the skin’s texture. These treatments are no longer limited to the face; they are now routinely used to rejuvenate the neck, hands, décolletage, and other body areas, helping restore volume, smooth uneven tone, and improve overall skin quality. This shift in focus reflects an increasing demand for more comprehensive skin rejuvenation that extends beyond traditional facial treatments.
Two standout options in the world of skin boosters are PhilArt and Profhilo. While both aim to enhance skin quality and hydration, they differ in their formulation, application techniques, and the specific types of results they deliver. Understanding these differences is crucial in selecting the right treatment for each patient’s unique needs.
In this article, we will delve into the differences between PhilArt and Profhilo, exploring how each works, the ideal candidates for these treatments, and the types of results patients can expect.
Key Takeaways
- PhilArt and Profhilo are two leading injectable treatments designed to improve skin quality, but they differ in composition and mechanism of action.
- PhilArt utilizes polynucleotides that stimulate fibroblast activity, enhancing collagen and elastin production over time, making it ideal for individuals with younger or sensitive skin seeking gradual regeneration.
- Profhilo contains a hybrid form of hyaluronic acid (HA), which provides both instant hydration and bioremodeling effects, making it best suited for mature skin with laxity, dehydration, and volume loss.
- Both treatments require 2-3 sessions, but Profhilo offers quicker visible effects, while PhilArt shows long-term improvements.
- Both have minimal side effects, with Profhilo offering a more subtle result and PhilArt providing faster skin tightening and plumping.
- PhilArt is especially effective for acne scars, delicate areas like the periorbital region, and photoaged skin, while Profhilo is commonly used for the mid/low face, neck, and décolletage.
- PhilArt offers gradual skin regeneration; Profhilo provides quicker hydration and firmness, with both being versatile and compatible for combined use.
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Polynucleotides vs Hybrid HA: How Each Product Works
PhilArt and Profhilo differ significantly in their composition and how they improve the skin. PhilArt uses polynucleotides—DNA fragments that stimulate fibroblasts, promote tissue repair, and reduce oxidative stress. This formulation supports long-term regeneration by enhancing cellular activity, leading to gradual improvements in skin texture and elasticity over time. Polynucleotides are especially beneficial for addressing skin aging at the cellular level.
On the other hand, Profhilo contains hybrid hyaluronic acid (HA) that spreads evenly under the skin. It delivers deep hydration, stimulates the production of collagen and elastin, and promotes the regeneration of the skin’s structure. This leads to enhanced firmness and elasticity.
While PhilArt works gradually with regenerative effects, Profhilo offers faster visible results through its combination of hydration and bioremodeling, making it a go-to for patients seeking quicker improvements in skin quality.
Patient Selection and Use Cases for PhilArt and Profhilo
Selecting the appropriate injectable treatment depends on the patient’s age, skin condition, and desired outcome. PhilArt and Profhilo share a common goal of skin rejuvenation and hydration, but their ideal candidates and use cases vary.
PhilArt
- Ideal Candidates: Best for individuals in their 20s to early 40s.
- Skin Concerns: Suitable for patients with early signs of aging, poor texture, or sensitive skin.
- Target Areas: Focuses on delicate zones like the periorbital region, lips, neck, and areas prone to skin aging.
- Use Cases: Primarily for preventive care, improving microcirculation, elasticity, and tone.
- Additional Benefits: Excellent for treating acne scars and photoaged skin.
- Treatment Goal: Gradual, long-term skin quality enhancement, ideal for those looking to prevent further aging signs.
Profhilo
- Ideal Candidates: Best for individuals in their late 30s to 60s.
- Skin Concerns: Particularly beneficial for patients experiencing moderate to advanced skin laxity, dehydration, and volume loss.
- Target Areas: Primarily used on the mid/lower face, neck, and décolletage.
- Use Cases: Focuses on hydration, skin tightening, and mild lifting without adding volume.
- Additional Benefits: Quick results with minimal invasiveness, making it ideal for busy patients.
- Treatment Goal: Visible rejuvenation, enhanced firmness, and improved skin texture for mature skin.
Protocols and Expected Results With PhilArt and Profhilo
PhilArt and Profhilo are applied through distinct protocols tailored to their specific formulations.
PhilArt Protocol
- Sessions: Typically 2–3 sessions spaced 3–4 weeks apart.
- Treatment Focus: Skin regeneration through the stimulation of collagen and elastin production using polynucleotides.
- Results: Gradual improvement in skin elasticity and texture over time.
- Ideal Use: Best for those looking for long-term skin improvement and subtle rejuvenation.
Profhilo Protocol
- Sessions: Typically 2 sessions, spaced 1 month apart, utilizing the BAP technique.
- Treatment Focus: Deep hydration, bioremodeling, and improving skin firmness through hyaluronic acid.
- Results: Quick radiance, skin plumping, and tightening effects after just a few sessions.
- Ideal Use: Suitable for those seeking immediate results without added volume.
Both treatments can also be combined for layered rejuvenation, which allows patients to address both structural needs and hydration for a more comprehensive aesthetic outcome.
Safety Profiles and Post-Treatment Considerations
Both PhilArt products and Profhilo come with a well-established safety profile. However, recovery experiences vary slightly.
- PhilArt: Typically causes minimal discomfort, with mild swelling or redness that resolves within 24 to 48 hours.
- Profhilo: May cause swelling or tenderness for up to 3 days, with occasional temporary lumps due to its broader diffusion.
Both treatments are low-risk and are formulated to be well-tolerated. Post-treatment recommendations for both include:
- Avoiding alcohol, makeup, and strenuous activities for 24 hours to ensure optimal healing.
- Massage and lymphatic drainage may be recommended if swelling persists.
Conclusion
PhilArt and Profhilo cater to different patient needs based on age, skin type, and desired treatment outcomes. PhilArt is ideal for younger or sensitive skin that requires gradual regeneration, especially in delicate areas. At the same time, Profhilo is well-suited for mature skin seeking hydration and firmness with quick results.
Both treatments provide non-volumizing rejuvenation, focusing on skin quality rather than contour changes. By understanding the distinct advantages of each treatment, clinicians can tailor their approach and deliver the best possible results for their patients.
FAQs
1. What is PhilArt made of?
PhilArt contains polynucleotides derived from purified salmon DNA, designed to stimulate tissue regeneration and fibroblast activity.
2. Is PhilArt safe for all skin types?
Yes, PhilArt is suitable for all Fitzpatrick skin types and is especially recommended for sensitive, thin, or aging skin.
3. How many sessions of PhilArt are needed?
A typical PhilArt protocol includes 3 to 4 sessions spaced 2 to 3 weeks apart, with results improving over time.
4. Can clinicians use PhilArt for under-eye rejuvenation?
Yes, PhilArt is ideal for the periorbital area and helps reduce dark circles, fine lines, and crepey skin texture.
5. What’s the difference between PhilArt and a filler?
PhilArt does not add volume like fillers. It regenerates skin tissue and improves quality without altering facial contours.
6. How long do PhilArt results last?
Results can last 6 to 12 months, depending on skin condition, age, and lifestyle, with maintenance sessions recommended.
7. Are there any side effects after PhilArt treatment?
Side effects are minimal and may include slight redness, swelling, or bruising, which typically resolve within a few days.
References
Vedamurthy M, Duvvuru V, Chelikani VL. Skin boosters – The upcoming boom in cosmetic dermatology for healthy skin. Cosmoderma. 2023;3:82. doi:10.25259/csdm_93_2023
Anjali. Can injectable strategies effectively rejuvenate the neck and decolletage for a youthful profile? Published March 11, 2024. https://www.icliniq.com/articles/skin-and-beauty/neck-and-decolletage-rejuvenation
Croma-Pharma introduces its newest injectable polynucleotide, PhilArt. Aesthetic Medicine. Published April 18, 2023. https://aestheticmed.co.uk/croma-pharma-introduces-its-newest-injectable
What Is Skin Rejuvenation? Verywell Health. https://www.verywellhealth.com/skin-rejuvenation-5120583
